Plague

Plague is a quarantine natural focal disease characterized with high fever, severe intoxication , appearing of bobos (necrotic changes in lymphatic glands, lungs and other organs) and sepsis. Pathogen is a motionless barrel shaped bacillus of plague. It is most dangerous infection. In nature it is saved due to periodic appearing of epizootic disease in gnawing animals who are major carriers of plague microbes (marmots, gopher).

The transmission of pathogen from animal to animal occurs via flea. A human gets infected with plague via contacting with diseased animals (skinning, meat cutting), consuming infected products, flea-bites, airbone. Human vulnerability is very high. Person diseased with plague is dangerous for other humans, especially when he suffers from pneumonic form of plague.

Symptoms
Incubation period lasts 3 – 6 days. The disease starts acutely with sudden chill and quick temperature increase to 40C. Chill is changed to fever, severe headache, dizziness, weakness, insomnia, nausea, vomit, muscle pains. Patient suffers from intoxication, impairment of consciousness, in some cases appear psychomotor agitation, delirium, hallucinations, lurch, redding of face and conjunctiva.

Face features become keen and appear dark circles under eyes. Skin is dry and hot to the touch, may appear petechiasis, large haemorrhages. Quickly are developed symptoms of cardio-vascular system damage, cardiac border widening, hollowness of tones, growing tachycardia, blood pressure drop, arrythmia, breathlessness, cyanosis.

The tongue has specific look: it is thick with breakings, covered with thick white accretion. Mouth mucosa is dry. Tonsils often are increased, have sores, on velum palatinum are found hemorrhages.In severe cases occurs frequent liquid stool with admixture of blood mucus. In urine may be found admixture of blood and protide.