Oral contraceptives and age of menarche affect the risk of asthma
Endogenous and exogenous sex hormones allegedly linked to the development of asthma and respiratory asthma-like disorders in young women, according to a team of researchers in the May issue of the Journal of Allergy and Clinical Immunology.
In the study, 905 were studied menstruating women aged 13 to 28 years old.
It was found that women with the appearance of menarche to 12 years, the risk of asthma after puberty was 2.08 times higher than in patients with the start of menarche at age 12 years.
Use of oral contraceptives is also correlated with an increase in the probability of occurrence of 1.75 in patients without a history of asthma, wheezing. It is not clear how the change in the level of sex hormones increases the risk of developing asthma. Perhaps this is due to unaccounted lifestyle factors, or is due to decrease in the content of physiological levels of estrogen and progesterone during phases of each menstrual cycle.
Data of previous large studies of postmenopausal women showed that hormone replacement therapy increases the risk of developing asthma. Oral contraceptives with higher doses of estrogen and progesterone can have a pronounced effect on asthma or asthma-like respiratory disorders.
However, the researchers argue that a combination of asthma and oral contraceptives have no contraindications.
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